Research Articles

• 2006 Sharma, N*, Brandis, K*, Herrera, SK*, Johnson, BE*, Vaidya, T*, Srestha, R*, and DebBurman, SK. Alpha-SYNUCLEIN BUDDING YEAST MODEL: Toxicity Enhanced By Impaired Proteasome and Oxidative Stress.
  Journal of Molecular Neuroscience 28, 171-178.
  PDF
• 2006 Brandis, K*, Holmes, I*, England, S*, Sharma, N*, Kukreja, L*, and DebBurman, SK. Alpha-SYNUCLEIN FISSION YEAST MODEL: Concentration-Dependent Aggregation Without Membrane Localization or Toxicity.
  Journal of Molecular Neuroscience 28, 179-192.
  PDF
• DebBurman, S.K. Learning How Scientists Work: Experiential research projects to promote cell biology learning and scientific process skills . Cell Biology Education 1(4), 154-162, 2002.
  html version | pdf version
• DebBurman, SK, Raymond, GJ, Caughey, B, & SL Lindquist (1997) Chaperone-supervised conversion of prion protein to its protease-resistant form. Proceedings of the National Academy of Sciences USA. 97, 13938-13943.
  PDF
  • Highlighted as Nature News & Views: by Welch, WJ, and P Gambetti. Nature 392, 23?24 (1998)
  • Highlighted in New Scientist This Week by Philip Cohen. New Scientist 2112, December 13, 1997, p8.
  • Highlighted in Folding & Design 3, 1998, R41 (as a new paper alert).
• DebBurman, SK, Ptasienski, J, Benovic, JL, & MM Hosey (1996). G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that is conditionally activated by G protein bg subunits. Journal of Biological Chemistry 271, 22552-22561.
  PDF
• DebBurman, SK, Ptasienski, J, Boetticher, E., Lomasney, JW, Benovic, JL, & MM Hosey (1995). Lipid-mediated regulation of G protein-coupled receptor kinases GRK2 & GRK3. Journal of Biological Chemistry 270, 5742-5747.
  PDF
• DebBurman, SK, Kunapuli, P, Benovic, JL, & MM Hosey (1995). Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases. Molecular Pharmacology 47, 224-233.

Undergraduate Journal Publications

• Zorniak, M* & Brandis, K* (Faculty Advisor: DebBurman, SK.) (2007) Can Oxidative Stress and Mitochondrial Dysfunction Enhance a-synuclein Toxicity in a Yeast Model of Parkinson’s Disease? Journal of Young Investigators Vol 17, issue 6. WebID: http://www.jyi.org/articletools/print.php?id=1350
  
• 2006 Paul, AG* (Faculty Advisor: DebBurman, SK.) Evaluation of STP2-dependent alpha-synuclein toxicity in a budding yeast model: Is GAPDH involved? Impulse (http://impulse.schc.sc.edu)

Invited Book Chapters

• Caughey, B, Chabry, J, Hermann, L, Demaimey, R, Raymond, G, Raymond, L, DebBurman, SK, Lindquist, SL, & B Chesebro (1999). Formation of protease-resistant prion protein: Stimulation and inhibition, in Alzheimer's Disease and Related Disorders (Edited by K Iqbal, DF Schwab, B Winblad, and HM Wisniewski), John Wiley & Sons, 581-587.
• Hosey, MM, DebBurman, SK, Pals-Rylaarsdam, R, & JL Benovic (1996). The Role of G protein-coupled receptor kinases in the regulation of muscarinic cholinergic receptors, in "Cholinergic mechanisms: From Molecular Biology to Clinical Significance" (Proceedings of the Ninth International Symposium on Cholinergic Mechanisms), Progress in Brain Research (Editors: K. Loffelholz and K. Klein), Elvesier, 236-253.

Invited Reviews

• Lindquist, SL, DebBurman, SK, Glover, JR, Kowal, AK, Liu, J, & TC Serio (1998). Amyloid fibers of Sup35 support a prion-like mechanism of inheritance in yeast. Biochemical Society Transactions 26, 486-90.
• DebBurman, SK, & MM Hosey (1995). Role of Protein Phosphorylation in the Desensitization of Muscarinic Cholinergic Receptors, in Molecular Mechanisms of Muscarinic Acetylcholine Receptor Function (Editor: J. Wess), R.G. Landes Company, Biomedical Publishers, Austin, USA, 209-226.
• Hosey, MM, Benovic, JL, DebBurman, SK, & RM Richardson (1995). Multiple mechanisms involving protein phosphorylation are linked to desensitization of muscarinic receptors, Proceedings of the Sixth International Symposium on Subtypes of Muscarinic Receptors) Life Sciences 11/12, 951-955.

In Preparation

• White, M*, Valtierra, S*, Kukreja, L*, Fiske, M*, Ayala, A*, Vahedi, M*, Herrera, S*, Brandis, K*, & DebBurman, SK. Two a--Synuclein Mutants E46K & A76E Offer Insight into Lipid Binding, Aggregation, and Toxicity in Yeast Models. Planned submission, June 2008.
• a-Synuclein Phosphorylation Mutants confer Toxicity. Planned submission, August 2008.
• DebBurman, SK, & Smith, P. The use of an undergraduate scholarship journal to strengthen undergraduate inquiry-based pedagogy and a community of student scholars. Planned submission to Cell Biology Education, 2009
• DebBurman, SK. Acting Out As Neuroscientists: Research Projects that Promote Undergraduate Neuroscience Learning & Process Skill Development. Planned submission to Journal of Undergraduate Neuroscience Education 2009
• DebBurman, SK. Acting Out As Neuroscientists: Experiential Research Projects that Promote Undergraduate Neuroscience Learning & Process Skill Development. Planned Submission 2006-2007
  (Progress in this work has been presented with published abstracts at the Society for Neuroscience Meeting 2003, Experimental Biology Meeting 2003, American Society of Biochemistry & Molecular Biology Meeting 2004)
• DebBurman, SK. Design of a Cell Biology Course Wherein Undergraduates Propose, Conduct, and Publish Original Research. Planned Submission 2007-2008.
  (Progress presented with published abstract at the Experimental Biology Meeting 2005 & American Society of Cell Biology Meeting 2005)

Ph.D. Thesis

• DebBurman, SK (1996). Phospholipids and G proteins Regulate Phosphorylation of Muscarinic Acetylcholine Receptors by G protein-coupled Receptor Kinases. Northwestern University.

Published Abstracts

• K. Brandis'06*, I. Holmes'05*, S. England'04*, N. Sharma'04*, L. Kukreja'08* S.K. DebBurman. Alpha-SYNUCLEIN FISSION YEAST MODEL: Concentration-Dependent Aggregation Without Membrane Localization or Toxicity. American Society of Cell Biology Meeting, San Francisco (2005)
• T. Vaidya'07*, K. Brandis'06*, S. Herrera'05*, N. Sharma'04*, T. Saylawala'08*, M. Vahedi'08*, S. Vahedi'08*, S.K. DebBurman. Alpha-SYNUCLEIN BUDDING YEAST MODEL: Toxicity Enhanced By Impaired Proteasome and Oxidative Stress. American Society of Cell Biology Meeting, San Francisco (2005)
• K. Brandis'06*, T. Vaidya'07*, & S.K. DebBurman. EUKARYON: An Undergraduate Journal of Life Science Scholarship at Lake Forest College. American Society of Cell Biology Meeting, San Francisco (2005)
• S.K. DebBurman. Design of a Cell Biology Course Wherein Undergraduates Propose, Conduct, and Publish Original Research. American Society of Cell Biology Meeting, San Francisco (2005)
• K. Brandis'06*, I. Holmes'05*, S. England'04*, SK DebBurman. Fission Yeast Recapitulate alpha-Synuclein Misfolding. Experimental Biology, San Diego, CA (2005)
• S.K. DebBurman. Design of a Cell Biology Course Wherein Undergraduates Propose, Conduct, and Publish Original Research. Experimental Biology, San Diego, CA (2005)
• S. Herrera'05*, N. Sharma'04*, B Johnson'03*, Brandis K'06*, R. Shrestha'07*, M. Stevenson'06*, S.K. DebBurman. Evaluating Protein Degradation Pathway and Post-translational Modification in Regulating alpha-Synuclein Misfolding in Yeast. Experimental Biology, San Diego, CA (2005)
• I. Holmes'05*, K. Brandis'06*, S. England'04*, S.K. DebBurman. Fission Yeast Recapitulate a-Synuclein Misfolding. American Society of Cell Biology Meeting, Washington DC (2004)
• S. Herrera'05*, N. Sharma'04*, B Johnson'03*, Brandis K'06*, R. Shrestha'07*, M. Stevenson'06*, S.K. DebBurman. Evaluating Protein Degradation Pathway and Post-translational Modification in Regulating alpha-Synuclein Misfolding in Yeast. American Society of Cell Biology Meeting, Washington DC (2004)
• S.K. DebBurman. Undergraduate Appreciation For Research In Medicine: Role-Playing Projects Using Primary Literature. Annual Meeting of the American Society of Biochemistry & Molecular Biology, Boston, MA (2004)
• Nijee Sharma'04*, Brandon Johnson'03*, Sara Herrera'05*, Shubhik DebBurman. Alpha-Synuclein Localizes to Cell Membrane and Forms Cytoplasmic Aggregates in Baker's Yeast. Annual Meeting of the American Society of Biochemistry & Molecular Biology, Boston, MA (2004)
• Isaac Holmes'05*, Samantha England'04*, Katrina Brandis'05*, Shubhik DebBurman. Schizosaccharomyces Pombe Model Recapitulates Alpha-Synuclein Misfolding. Annual Meeting of the American Society of Biochemistry & Molecular Biology, Boston, MA (2004)
• Nijee Sharma'04*, Samantha England'04*, Isaac Holmes'05*, Katrina Brandis'06*, Brandon Johnson'03*, Shubhik DebBurman. Developing Two Yeast Models for Protein Misfolding Linked to Parkinson’s Disease. American Society of Cell Biology Annual Meeting, San Francisco, CA (December 2003)
• S.K. DebBurman. Appreciating The Role Of Research In Medicine & Society: Experiential Research Projects For
  Beginning, Intermediate, And Advanced Undergraduates. American Society of Cell Biology Annual Meeting, San Francisco, CA (December 2003)
• *Brandon Johnson'03, *Nijee Sharma'04, Shubhik DebBurman. (2003) Expression of wildtype and mutant alpha-synuclein in Baker’s Yeast. Annual Meeting of the American Society of Biochemistry & Molecular Biology.
• DebBurman, SK. (2003)THINKING LIKE A SCIENTIST: Experiential Research Projects To Promote Undergraduate Biology Learning And Scientific Process Skills. Annual Meeting of the American Society of Biochemistry & Molecular Biology.
• DebBurman, SK (2002). Mock experiential research projects requiring primary article comprehension promote student learning in an undergraduate neurobiology course. Molecular Biology of the Cell.
• DebBurman, SK (2002). Experiential research projects requiring primary article mastery promotes student learning in an undergraduate neurobiology course. Society for Neuroscience Abstracts.
• DebBurman, SK (2002). Experiential research projects promote learning an inquiry-based undergraduate science curriculum. NCUR 2002 Conference Proceedings.
• DebBurman, SK (2002). Experiential research projects promote learning an inquiry-based undergraduate science curriculum. Faseb Journal, late breaking abstracts.
• DebBurman, SK (2001). Experiential projects promote learning via mastery of primary articles in two undergraduate cell biology courses. Molecular Biology of the Cell.
• DebBurman, SK (2000). Mastering primary articles: Two experiential projects that enhance learning among undergraduate science majors. FASEB Journal Abstracts.
• DebBurman, SK., & S.L. Lindquist (2000). Chaperone-promoted solubilization of PrP-res. FASEB Journal Abstracts.
• DebBurman, SK, & S.L. Lindquist (1998). Chaperone-promoted solubilization of PrP-res, the infectious element in transmissible spongiform encephalopathies. Molecular Biology of the Cell.
  Featured in 1998-99 ASCB Press Book/Web Page (selected as one of the noteworthy cell biology research abstracts
  http://www.ascb.org/meetings/pressbk98.pdf
• DebBurman, SK, Caughey, B, & SL Lindquist (1998). Molecular chaperones and mammalian prion formation. Journal of Investigative Medicine.
• DebBurman, SK, Raymond, GJ, Caughey, B, & Lindquist, SL (1997). Chaperone-mediated conversion of cellular prion protein to its protease-resistant form. FASEB Journal Abstracts.
• DebBurman, SK, Ptasienski, J, & MM Hosey (1995). Effects of phospholipids on agonist-dependent phosphorylation of human m2 muscarinic receptors by G protein-coupled receptor kinases: An alternate mode to kinase activation? Life Sciences.
• DebBurman, SK, Ptasienski, J, and MM Hosey (1994). Agonist-dependent phosphorylation of muscarinic acetylcholine receptors by G protein-coupled receptor kinases. Society for Neurosciences Abstracts.
• DebBurman, SK, & MM Hosey (1994). Agonist-dependent phosphorylation of human m2 muscarinic acetylcholine receptors in Sf9 insect cell membranes. Biophysics Abstracts.